Augsburger J J, Mullen D, Kleineidam M
Oncology Unit, Wills Eye Hospital, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pa 19107.
Ophthalmic Surg. 1993 Feb;24(2):76-81.
We studied the short-term impact of planned sequential episcleral I-125 plaque irradiation and indirect ophthalmoscope laser therapy in a series of 25 patients with choroidal or ciliochoroidal malignant melanoma. In a case-by-case matched comparison study, we evaluated the relative local regression of tumors which did and did not receive planned supplemental laser therapy following plaque treatment. The tumors treated with supplemental laser regressed substantially faster and more completely than those treated by plaque alone. Planned sequential I-125 plaque irradiation combined with indirect ophthalmoscope laser therapy appears to be a more effective local-tumor treatment than plaque radiotherapy alone.
我们研究了计划性巩膜外 I-125 敷贴放疗联合间接检眼镜激光治疗对 25 例脉络膜或睫状体脉络膜恶性黑色素瘤患者的短期影响。在一项逐例匹配对照研究中，我们评估了接受和未接受敷贴治疗后计划性补充激光治疗的肿瘤的相对局部消退情况。接受补充激光治疗的肿瘤比仅接受敷贴治疗的肿瘤消退得更快且更完全。计划性序贯 I-125 敷贴放疗联合间接检眼镜激光治疗似乎比单纯敷贴放疗更有效地治疗局部肿瘤。
