Björnberg A, Löwhagen G B, Tengberg J E
Acta Derm Venereol. 1979;59(1):49-53.
98 workers at a glass-wool factory were divided into three comparable groups: those with persistent troublesome itching from the fibres, those without itching, and those who had become 'hardened' to the itching. The three groups were compared with respect to the results of patch testing with glass fibres and six chemical irritants, a rubbing test with fibres, the Trafuril test, and provocation of dermographism. Anamnestic data with respect to atopy, itching from wool and synthetic fibres, sweating, and reactions to the sun were evaluated, as also was the general skin pigmentation. No statistically significant differences between the three groups were found in respect of any of these tests or factors except for a subjectively increased sensitivity in the rubbing test with fibres for the itching group. It is possible that similar itch-provocation tests might be useful for pre-employment assessment to predict severe occupational itching from glass fibres.
一家玻璃棉工厂的98名工人被分成三个可比组：因纤维而持续出现严重瘙痒的工人、无瘙痒症状的工人以及对瘙痒“耐受”的工人。对这三组工人进行了比较，比较内容包括玻璃纤维和六种化学刺激物的斑贴试验结果、纤维摩擦试验、特拉呋利试验以及皮肤划痕症激发试验。评估了关于特应性、羊毛和合成纤维引起的瘙痒、出汗以及对阳光反应的既往数据，还评估了一般皮肤色素沉着情况。除了瘙痒组在纤维摩擦试验中主观感觉敏感性增加外，在这些试验或因素方面，三组之间未发现统计学上的显著差异。类似的瘙痒激发试验可能有助于入职前评估，以预测因玻璃纤维导致的严重职业性瘙痒。
