HAGBERG L, Nilsson B E
Geriatrics. 1977 Apr;32(4):55-8, 61.
Hip radiograms made 15 to 25 years previously in 39 women were examined. These women were between 58 and 62 years old when the first radiogram was made, and all sustained cervical or trochanteric fracture of the upper end of the femur on an average of 14 years later. The trabecular pattern of the upper end of the femur was classifed according to Singh, and the medial cortex of the femoral neck was measured and expressed as a fraction of the total width (femoral neck index). For comparison, the same information was collected from a control sample of films taken during the same period in women who did not sustain subsequent hip fracture. The cortex was thinner in women who later had hip fracture than in control women. Women with coxarthrosis had the highest cortical ratio. The trabecular pattern in women who later had hip fracture shifted in the direction of osteoporosis in comparison with the controls. It was not possible to predict from either measurement which hip would fracture or when fracture would occur. This study demonstrates that by using only simple measurements on hip radiograms, it might be possible to include in a sample of women selected for a therapeutic trial those who are likely to sustain hip fracture.
对39名女性15至25年前拍摄的髋部X光片进行了检查。首次拍摄X光片时，这些女性年龄在58至62岁之间，平均14年后均发生了股骨上端的颈椎或转子骨折。根据辛格的方法对股骨上端的小梁模式进行分类，并测量股骨颈内侧皮质，并将其表示为总宽度的分数（股骨颈指数）。为了进行比较，从同期拍摄的未发生后续髋部骨折的女性对照样本中收集了相同信息。后来发生髋部骨折的女性的皮质比未发生骨折的对照女性更薄。患有髋关节炎的女性皮质比率最高。与对照组相比，后来发生髋部骨折的女性的小梁模式向骨质疏松方向转变。无论是通过哪种测量方法，都无法预测哪一侧髋部会骨折或何时会发生骨折。这项研究表明，仅通过对髋部X光片进行简单测量，就有可能在选择进行治疗试验的女性样本中纳入那些可能发生髋部骨折的女性。
