Greenspan S L, Myers E R, Maitland L A, Kido T H, Krasnow M B, Hayes W C
Department of Medicine, Beth Israel Hospital, Boston, Massachusetts.
J Bone Miner Res. 1994 Dec;9(12):1889-94. doi: 10.1002/jbmr.5650091208.
Hip fractures can be separated into femoral neck (cervical or intracapsular) or trochanteric (extracapsular). Trochanteric fractures have been associated with up to twice the short-term mortality of cervical fractures in the elderly. Fracture type may be influenced by the fall direction and local differences in proximal femur strength properties. We previously demonstrated that fall characteristics and body habitus, in addition to femoral bone mineral density, play a dominant role in the prediction of hip fracture in elderly fallers. To examine the association of these determinants with hip fracture type, we assessed fall characteristics, body habitus, and site-specific bone mineral density measurements in 112 elderly hip fracture patients (85 women and 27 men, mean age 85 years) 1 week after an acute hip fracture. Trochanteric BMD was 13% lower in women and 11% lower in men for patients with trochanteric fracture than in those with femoral neck fracture (p < 0.01). A stepwise multiple logistic regression indicated that trochanteric BMD (decrease of 1.0 SD, adjusted OR 4.6, 95% Cl 2.0-9.5, p < 0.0001) and femoral neck BMD (increase of 1.0 SD, adjusted OR 3.0, 95% Cl 1.6-5.9, p = 0.0003) were independently associated with trochanteric fracture. Fall characteristics, body habitus, gender, and age were not associated with hip fracture type. We conclude that a relatively low trochanteric BMD or a high femoral neck BMD was associated with a trochanteric hip fracture and that site-specific trochanteric BMD determinations should be measured when assessing risk of trochanteric hip fractures in the elderly.
髋部骨折可分为股骨颈(颈或囊内)骨折或转子间(囊外)骨折。在老年人中,转子间骨折的短期死亡率高达颈骨折的两倍。骨折类型可能受跌倒方向和股骨近端强度特性的局部差异影响。我们之前证明,除股骨骨密度外,跌倒特征和身体形态在老年跌倒者髋部骨折的预测中起主导作用。为了研究这些决定因素与髋部骨折类型的关联,我们在112例老年髋部骨折患者(85名女性和27名男性,平均年龄85岁)急性髋部骨折1周后,评估了跌倒特征、身体形态和特定部位的骨密度测量值。与股骨颈骨折患者相比,转子间骨折患者的女性转子间骨密度低13%,男性低11%(p<0.01)。逐步多元逻辑回归表明,转子间骨密度(降低1.0标准差,调整后OR 4.6,95%CI 2.0-9.5,p<0.0001)和股骨颈骨密度(增加1.0标准差,调整后OR 3.0,95%CI 1.6-5.9,p = 0.0003)与转子间骨折独立相关。跌倒特征、身体形态、性别和年龄与髋部骨折类型无关。我们得出结论,相对较低的转子间骨密度或较高的股骨颈骨密度与转子间髋部骨折相关,并且在评估老年人转子间髋部骨折风险时应测量特定部位的转子间骨密度。