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[基层医疗中苯二氮䓬类药物的处方情况]

[Prescription of benzodiazepines in general practice].

作者信息

Bjerrum L, Christensen P B, Larsen P H

机构信息

Odense Universitet, Institut for Helsetjenesteforskning og Sygdomsforebyggelse, Almen Medicin.

出版信息

Ugeskr Laeger. 1993 Feb 1;155(5):315-9.

PMID:8447003
Abstract

General practitioners are responsible for about 90% of all prescriptions for psychotropic drugs which benzodiazepines account for approximately 75%. In order to obtain a quantitative and qualitative assessment of the consumption in Svendborg, all benzodiazepine prescriptions were registered during a two-month period (February and March 1990). A total of 3364 prescriptions were issued to 6% (2262 persons) of the population. Of these, 1837 (54.6%) were prescriptions for tranquillizers, 1272 (37.8%) for hypnotics and 255 (7.6%) for both tranquillizers and hypnotics. The prevalence of benzodiazepine users increased with age and women were responsible for about 2/3 of the total consumption. Small but frequent prescriptions were issued to the younger users of benzodiazepines while older users generally received prescriptions for greater quantities at longer intervals. One in four persons over 80 years of age used sedatives. On account of the pharmaceutical, social and economic consequences of the widespread use of benzodiazepines in the elderly population, restrain should be observed in prescribing benzodiazepines.

摘要

全科医生开出了约90%的精神药物处方,其中苯二氮䓬类药物约占75%。为了对斯文堡的药物消费进行定量和定性评估,在两个月的时间里(1990年2月和3月)记录了所有苯二氮䓬类药物的处方。总共开出了3364张处方,涉及6%的人口(2262人)。其中,1837张(54.6%)是镇静剂处方,1272张(37.8%)是催眠药处方,255张(7.6%)既是镇静剂又是催眠药的处方。苯二氮䓬类药物使用者的患病率随年龄增长而增加,女性约占总消费量的2/3。苯二氮䓬类药物年轻使用者的处方量小但开具频繁,而老年使用者通常间隔更长时间开具更大剂量的处方。80岁以上的人中有四分之一使用镇静剂。鉴于苯二氮䓬类药物在老年人群中广泛使用的药物、社会和经济后果,在开具苯二氮䓬类药物时应谨慎。

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