Holm M
Institute of General Practice, University of Aarhus, Denmark.
Dan Med Bull. 1988 Oct;35(5):495-9.
During one week in 1985, 227 general practitioners in the County of Arhus, Denmark, recorded their prescriptions of benzodiazepines. In all 2,812 prescriptions were recorded, for 2,574 patients. The sex ratio (male/female) was 1.0/2.0. The incidence of first-time prescriptions was 26.0 prescriptions/1,000 inhabitants/year. The prescription rate, calculated as defined daily doses/1,000 inhabitants/day, was highest for minor tranquillizers in the age group 60-69, whereas for hypnotics/sedatives it was highest in the age group 70+. Of minor tranquillizers, 83-84% were prescribed as anxiolytics, and of hypnotics/sedatives, 98% were prescribed as hypnotics. Only 18-28% of patients had a diagnosis of psychiatric illness. Between 62-75% of patients received no other treatment than a benzodiazepine prescription. At the time of the first prescriptions, 44-57% of the patients were mentally distressed. For about 33% of patients, a somatic illness was of essential importance for the prescription. Twenty-six percent of the men and 17% of the women taking benzodiazepines were recognized as real or potential abusers. Eighty-three percent of repeat prescriptions were prescribed through indirect contacts.
1985年的某一周,丹麦奥胡斯郡的227名全科医生记录了他们开出的苯二氮䓬类药物处方。总共记录了2812张处方,涉及2574名患者。男女比例为1.0/2.0。首次处方的发生率为26.0张处方/1000居民/年。以限定日剂量/1000居民/天计算的处方率,在60 - 69岁年龄组中,小剂量镇静剂最高,而在70岁及以上年龄组中,催眠药/镇静剂最高。在小剂量镇静剂中,83 - 84%被开为抗焦虑药,在催眠药/镇静剂中,98%被开为催眠药。只有18 - 28%的患者被诊断患有精神疾病。62 - 75%的患者除了苯二氮䓬类药物处方外没有接受其他治疗。在首次开处方时,44 - 57%的患者存在精神困扰。约33%的患者,躯体疾病对处方起着至关重要的作用。服用苯二氮䓬类药物的男性中有26%,女性中有17%被认定为实际或潜在的滥用者。83%的重复处方是通过间接联系开出的。