Hansen T G, Henneberg S W, Hole P
Anaestesi- og intensiv afdeling V, Odense Sygehus.
Ugeskr Laeger. 1993 Feb 8;155(6):390-4.
In order to introduce intravenous patient-controlled analgesia (PCA) in children in the Department of Anaesthesiology and Intensive Care, Odense University Hospital, we evaluated the technique in 13 children following major orthopaedic or abdominal surgery. The pump (Pharmacia-Deltec, CADD-PCA) was loaded with 1 mg/ml morphine in a 50 milliliters cassette. A bolus dose of 25 micrograms/kg and a lock-out interval of eight minutes were the initial settings. The morphine dose used, pain scores and side effects were currently recorded. Ages ranged from 4-15 years (mean 10.5 years) and the method was used for a mean of 89 hours (range 57-144 hours) postoperatively. Morphine requirements averaged 9.5 microgram/kg/hour (range 5.4-15.6 microgram/kg/hour). Pain control was good and side effects were few and of minor nature. PCA is an effective and safe means of providing good quality analgesia in children.
为了在欧登塞大学医院麻醉与重症监护科引入儿童静脉自控镇痛（PCA）技术，我们对13例接受大型骨科或腹部手术的儿童进行了该技术评估。泵（法玛西亚-德尔泰克，CADD-PCA）的50毫升药盒中装入了1毫克/毫升的吗啡。初始设置为推注剂量25微克/千克，锁定间隔时间为8分钟。记录当前使用的吗啡剂量、疼痛评分和副作用。年龄范围为4至15岁（平均10.5岁），该方法在术后平均使用89小时（范围57至144小时）。吗啡需求量平均为9.5微克/千克/小时（范围5.4至15.6微克/千克/小时）。疼痛控制良好，副作用少且程度轻微。PCA是为儿童提供高质量镇痛的一种有效且安全的方法。
