隐孢子虫在犬肾Madin-Darby细胞中发育的超微结构研究。
Ultrastructural study of Cryptosporidium development in Madin-Darby canine kidney cells.
作者信息
Rosales M J, Mascaro C, Osuna A
机构信息
Department of Molecular Parasitology, Faculty of Sciences, University of Granada, Spain.
出版信息
Vet Parasitol. 1993 Jan;45(3-4):267-73. doi: 10.1016/0304-4017(93)90081-w.
PMID:8447069
Abstract
Transmission electron microscope studies have been made into phases of the life cycle of a bovine isolate of Cryptosporidium cultured in vitro on Madin-Darby canine kidney cells. The cytoplasm of parasitized cells was noticeably altered, including marked vacuolization and the appearance of membrane structures close to the developing parasites. These changes suggest that the protozoan may release cytopathogenic factors.
摘要
已利用透射电子显微镜对一种在Madin-Darby犬肾细胞上进行体外培养的牛隐孢子虫分离株生命周期的各个阶段进行了研究。被寄生细胞的细胞质发生了明显变化，包括显著的空泡化以及在发育中的寄生虫附近出现膜结构。这些变化表明该原生动物可能释放细胞致病因子。
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