Ellis T M, Masters A M, Sutherland S S
Animal Health Division, Department of Agriculture, South Perth, WA, Australia.
Vet Microbiol. 1993 Jan;34(1):63-9. doi: 10.1016/0378-1135(93)90007-t.
Merino ewes lambs from a flock expected to have a high prevalence of dermatophilosis were examined for lesions at marking, weaning and prior to first shearing. Blood was collected at marking and prior to shearing to enable quantification of T6-lymphocyte antigen levels in peripheral blood mononuclear cells (PBM) using monoclonal antibody SBU-T6 20-27. A group of the lambs that had persistent and/or severe dermatophilosis had significantly lower (P < 0.05) mean levels of T6-lymphocyte staining in PBM than those with minimal or no dermatophilosis in blood samples collected prior to shearing. However, the wide variability of this parameter in resistant and susceptible lambs indicated that this would not be a satisfactory procedure to rank sheep for resistance to dermatophilosis.
对一群预计嗜皮菌病患病率较高的美利奴母羊及其羔羊在打号、断奶时以及首次剪毛前进行了病变检查。在打号时和剪毛前采集血液，以便使用单克隆抗体SBU-T6 20-27对外周血单核细胞（PBM）中的T6淋巴细胞抗原水平进行定量分析。在剪毛前采集的血样中，一组患有持续性和/或严重嗜皮菌病的羔羊，其PBM中T6淋巴细胞染色的平均水平显著低于（P < 0.05）那些患有轻微嗜皮菌病或无嗜皮菌病的羔羊。然而，该参数在抗性和易感羔羊中的广泛变异性表明，这不是对绵羊抗嗜皮菌病能力进行排名的令人满意的方法。
