西班牙巴斯克人和邻近人群的人类白细胞抗原（HLA）频率。

HLA frequencies in Basques in Spain and in neighbouring populations.

作者信息

Calderon R, Wentzel J, Roberts D F

机构信息

Departamento de Biologia Animal y Genetica, Universidad del Pais Vasco, Bilbao, Spain.

出版信息

Ann Hum Biol. 1993 Mar-Apr;20(2):109-20. doi: 10.1080/03014469300002562.

DOI:10.1080/03014469300002562

PMID:8447656

Abstract

HLA antigen and gene frequencies at the A, B, and C loci are examined in a sample of 181 Basques and 102 non-Basques in Bilbao, Spain. The most common associations of genes at the A and B loci are as in western Europe generally. The results are compared with gene frequencies in other Basque and non-Basque samples in Spain and France. There is clear distinction in gene frequency between Basques and non-Basques, to which the greatest contribution is made by A1 and B35, followed by B7, B8 and B12; and a difference between Basques in France and in Spain, notably in A28, 29, 30 and 31 and B17 and 18.

摘要

在西班牙毕尔巴鄂的181名巴斯克人和102名非巴斯克人的样本中，检测了A、B和C位点的HLA抗原及基因频率。A和B位点基因的最常见组合与西欧总体情况相同。将结果与西班牙和法国其他巴斯克及非巴斯克样本的基因频率进行了比较。巴斯克人和非巴斯克人之间在基因频率上有明显差异，其中A1和B35贡献最大，其次是B7、B8和B12；法国和西班牙的巴斯克人之间也存在差异，特别是在A28、29、30和31以及B17和18方面。