Reisler E
Department of Chemistry and Biochemistry, University of California, Los Angeles 90024-1570.
Curr Opin Cell Biol. 1993 Feb;5(1):41-7. doi: 10.1016/s0955-0674(05)80006-7.
The understanding of actin structure and function has been improved by comparing the atomic structure of G-actin, the model of the F-actin structure, and the properties of actin mutants. Several aspects of actin structure have been tested and good progress has been made in mapping its myosin-binding sites. The dynamic properties of actin and genetic evaluation of its cellular function are attracting increasing attention.
通过比较G-肌动蛋白的原子结构、F-肌动蛋白结构模型以及肌动蛋白突变体的特性,人们对肌动蛋白的结构和功能有了更深入的理解。肌动蛋白结构的几个方面已经得到验证,并且在绘制其肌球蛋白结合位点方面取得了良好进展。肌动蛋白的动态特性及其细胞功能的遗传学评估正受到越来越多的关注。