Tan G, Kaufman L, Peterson E M, de la Maza L M
Department of Pathology, University of California, Irvine, Orange 92668.
Clin Infect Dis. 1993 Jan;16(1):107-11. doi: 10.1093/clinids/16.1.107.
Two men with AIDS developed fungal infections and subsequently died as a result of dissemination of the fungal infection. Findings obtained by histologic examination, serological studies, and cultures suggested that the infections were caused by Blastomyces dermatitidis. Tissue sections showed polymorphic yeast-like cells 5-20 microns in diameter (some with broad and others with narrow single- or multiple-based buds), small yeasts, and hyphal elements. The exoantigen K positivity and exoantigen A negativity of one of the isolates indicated that the fungus was more like an African than a North American serotype.
两名艾滋病患者发生真菌感染，随后因真菌感染播散而死亡。组织学检查、血清学研究和培养结果提示感染由皮炎芽生菌引起。组织切片显示直径5-20微米的多形性酵母样细胞（有些有宽的，有些有窄的单基或多基芽）、小酵母和菌丝成分。其中一株分离株的外抗原K阳性和外抗原A阴性表明该真菌更像非洲血清型而非北美血清型。
