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毛果芸香碱对慢性血液透析患者皮肤电阻的影响。

The effect of pilocarpine on electrodermal resistance in chronic hemodialyzed patients.

作者信息

Marczewski K, Janicka L, Cudny J

机构信息

Clinic of Nephrology, Medical Academy, Lublin, Poland.

出版信息

Clin Nephrol. 1993 Feb;39(2):88-91.

PMID:8448923
Abstract

Electric resistance of forearm skin was examined in 40 hemodialyzed (HD) patients under resting conditions and after subjecting the skin to the action of a 10% pilocarpine gel. The results were compared with a control group of a 100 healthy volunteers. An increased skin resistance was observed before dialysis and then a significant post-dialysis fall to the normal level followed. The response to the applied pharmacological stimulus in the HD group was similar to that in the control group. The results suggest that the rise in skin resistance in patients with renal failure and the so-called uremic dry skin, are not connected with the dysfunction of the glands themselves but rather with their insufficient stimulation.

摘要

在40名接受血液透析(HD)的患者处于静息状态时以及在其皮肤受到10%毛果芸香碱凝胶作用后,对其前臂皮肤的电阻进行了检测。将结果与由100名健康志愿者组成的对照组进行了比较。在透析前观察到皮肤电阻增加,随后透析后显著下降至正常水平。HD组对所施加的药理刺激的反应与对照组相似。结果表明,肾衰竭患者皮肤电阻的升高以及所谓的尿毒症性皮肤干燥,并非与腺体本身的功能障碍有关,而是与其刺激不足有关。

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