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Seroepidemiology of hepatitis B and D virus infection among intravenous drug addicts in Israel.

作者信息

Dan M, Rock M, Lilos P, Shany S B

机构信息

Infectious Diseases Unit, E Wolfson Hospital, Holon, Israel.

出版信息

Int J Epidemiol. 1993 Feb;22(1):140-3. doi: 10.1093/ije/22.1.140.

DOI:10.1093/ije/22.1.140
PMID:8449634
Abstract

To evaluate the prevalence of hepatitis B virus (HBV) and hepatitis D virus (HDV) infection among intravenous drug addicts (IVDA) in Israel, serum samples were collected from 400 asymptomatic individuals attending a methadone clinic in Tel Aviv. Overall 5.5% were HBsAg positive, 2.4% HBeAg positive, 52% anti-HBc positive and 6.6% were positive for anti-HD. Anti-HD was identified in 18% of addicts who were HBsAg positive and in 3% who were HBsAg negative and anti-HBc positive. Strong correlation was found between positivity to HBV antibodies and age and duration of drug use. History of jaundice correlated more strongly with anti-HD positivity than with presence of antibodies to HBV. We conclude that Israeli IVDA are less exposed to HBV and HDV infection than their North American and European counterparts.

摘要

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