海星皂苷，第49部分。来自多棘海盘车的新型细胞毒性甾体糖苷。

Starfish saponins, part 49. New cytotoxic steroidal glycosides from the starfish Fromia monilis.

作者信息

Casapullo A, Finamore E, Minale L, Zollo F

机构信息

Dipartimento di Chimica della Sostanze Naturali, Università degli Studi di Napoli "Federico II.", Italy.

出版信息

J Nat Prod. 1993 Jan;56(1):105-15. doi: 10.1021/np50091a015.

DOI:10.1021/np50091a015

PMID:8450314

Abstract

Nine new cytotoxic steroidal glycosides 1-9 have been isolated from the starfish Fromia monilis collected off New Caledonia. Structures of these compounds, which include four mono-(1-4), two di-(5,6), and three glycosides (7-9), were elucidated through spectral interpretation. Monilosides G [7], H [8], and I [9] are the first tri-glycosides to be found among the group of glycosides of polyhydroxilated steroids from starfishes.

摘要

从新喀里多尼亚海域采集的多棘海盘车（Fromia monilis）中分离出了9种新的细胞毒性甾体糖苷1-9。通过光谱解析阐明了这些化合物的结构，其中包括4种单糖苷（1-4）、2种二糖苷（5,6）和3种三糖苷（7-9）。多棘海盘车苷G [7]、H [8]和I [9]是海星多羟基甾体糖苷类中首次发现的三糖苷。