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暂时性棘层松解性皮病(格罗弗病)

Transient acantholytic dermatosis (Grover).

作者信息

Wolff H H

出版信息

Hautarzt. 1977 Feb;28(2):78-82.

PMID:845033
Abstract

The clinical, histopathological, and electron microscopical characteristics of "transient acantholytic dermatosis" (Grover, 1971) are described. Clinically, there are papules with smooth or keratotic surfaces and sometimes papulovesicles. The lesions are mainly distributed on the trunk predominantly of male patients past the age of 40. The disease usually disappears within weeks, but rarely may be protracted. Histologically, focal changes with the epidermis of Dariertype, Hailey-Hailey-type, pemphigus (vulgaris or foliaceus)-type, or spongiotic-acantholytic type, often in combination, are found. This disease seems to be common. Its distinctiveness should be confirmed by further observations.

摘要

描述了“暂时性棘层松解性皮病”(格罗弗,1971年)的临床、组织病理学和电子显微镜特征。临床上,有表面光滑或角化的丘疹,有时还有丘疱疹。皮损主要分布于躯干,以40岁以上男性患者为主。该病通常在数周内消失,但很少会迁延不愈。组织学上,常可见到局灶性改变,表现为达里埃型、黑利-黑利型、天疱疮(寻常型或落叶型)型或海绵状棘层松解型表皮改变,且常为多种改变并存。这种疾病似乎很常见。其独特性应通过进一步观察来证实。

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