Degtyarenko A M, Zavadskaya T V, Baev K V
Department of Physiology of the Spinal Cord, A. A. Bogomoletz Institute of Physiology, Ukrainian Academy of Sciences, Kiev.
Neuroscience. 1993 Jan;52(2):323-32. doi: 10.1016/0306-4522(93)90160-h.
In experiments on immobilized decerebrate cats, data about reorganization of efferent activity parameters of the forelimb and hindlimb locomotor generators evoked by electrical stimulation of descending systems were obtained. The generators controlling both forelimb and hindlimb locomotor movements were found to be characterized by the existence of stable states at which total influence of different descending systems on these generators was extremely limited. These data enable us to conclude that the sense of activity reorganization in locomotor generators of both forelimb and hindlimb under the influence of descending system signals is in bringing the motor program to a dynamic relation with supraspinal inflow, where a sufficient degree of limitation and balancing of the influences of corresponding descending systems on the interneuronal nets, determining time and phase characteristics of these generators, is ensured. Possible mechanisms of realization of this interaction between descending signals and locomotor activity generators are discussed.
在对固定去大脑猫的实验中，获得了关于电刺激下行系统所诱发的前肢和后肢运动发生器传出活动参数重组的数据。发现控制前肢和后肢运动的发生器具有稳定状态，在这些状态下，不同下行系统对这些发生器的总体影响极为有限。这些数据使我们能够得出结论，在前肢和后肢运动发生器受下行系统信号影响时活动重组的意义在于使运动程序与脊髓上输入建立动态关系，在这种关系中，相应下行系统对中间神经元网络的影响有足够程度的限制和平衡，从而确保了这些发生器的时间和相位特征。文中还讨论了下行信号与运动活动发生器之间这种相互作用实现的可能机制。
