Sachdev P, Loneragan C
Neuropsychiatric Institute, Prince Henry Hospital, Sydney, Australia.
Neurology. 1993 Mar;43(3 Pt 1):544-7. doi: 10.1212/wnl.43.3_part_1.544.
We challenged seven tardive akathisia patients with low-dose apomorphine (0.01 mg/kg) SC and placebo in a double-blind, random design. Apomorphine caused a significantly greater reduction in the objective (movement) but not the subjective (distress) component of akathisia.
我们采用双盲、随机设计,让7名迟发性静坐不能患者皮下注射低剂量阿扑吗啡(0.01毫克/千克)和安慰剂。阿扑吗啡使静坐不能的客观(运动)成分显著减少,但主观(痛苦)成分未减少。