Rieg T S, Doerries L E, O'Shea J G, Aravich P F
Eastern Virginia Medical School, Norfolk.
Physiol Behav. 1993 Mar;53(3):607-10. doi: 10.1016/0031-9384(93)90161-8.
Rats given restricted feeding and allowed free access to activity wheels increase activity, decrease food intake, and lose body weight compared to nonexercised controls. The phenomenon is of interest because of the relationship between exercise and anorexia nervosa. This study determined if another factor that energizes behavior in rats, water deprivation, produces similar exercise-induced weight loss. Rats were maintained on a restricted water schedule (10 min/day) combined with free access to running wheels and food; controls had no wheel access or were food deprived only. Both water-deprived groups consumed similar amounts of food and water, with the exercised group losing more body weight. Plasma osmolality, hematocrit, and posterior pituitary vasopressin content were equivalent in the two water-deprived groups, indicating similar hydrational status. It is concluded that the weight loss effect in water-deprived rats is due to excessive voluntary exercise, and that other factors that energize behavior should produce a similar effect.
与不运动的对照组相比，限制进食并允许自由使用活动轮的大鼠活动增加、食物摄入量减少且体重减轻。由于运动与神经性厌食症之间的关系，这一现象备受关注。本研究确定了另一个激发大鼠行为的因素——缺水，是否会产生类似运动引起的体重减轻。大鼠维持在限制饮水时间表（每天10分钟），并可自由使用跑步轮和食物；对照组无法使用轮子或仅限制食物摄入。两个缺水组消耗的食物和水量相似，但运动组体重减轻更多。两个缺水组的血浆渗透压、血细胞比容和垂体后叶加压素含量相当，表明水合状态相似。研究得出结论，缺水大鼠的体重减轻效应是由于过度的自主运动，其他激发行为的因素也应产生类似的效果。
