Yanagida M, Ushiro K, Yamashita T, Kumazawa T, Katoh T
Department of Otolaryngology, Kansai Medical University, Osaka, Japan.
Acta Otolaryngol Suppl. 1993;500:58-61. doi: 10.3109/00016489309126181.
Enhanced MRI was performed in 14 patients with Ramsay-Hunt's syndrome to investigate the pathogenesis of this syndrome. All MRI studies were performed on a 0.5T superconductivity MRI system using a head coil with Gd-DTPA. Enhancement was observed in the areas of the distal internal auditory canal and labyrinthine segment in many patients, and was especially prominent in patients suffering from vertigo, tinnitus, and hearing loss. In some patients it involved not only the facial nerve of the internal auditory canal but also the cochlear nerve and vestibular nerves. Since histological changes of the facial nerve in patients with Ramsay-Hunt's syndrome are assumed to occur in the distal internal auditory canal and labyrinthine segment, which is more proximal than the geniculate ganglion, and the possibility is suggested that inflammation may spread to the vestibular and cochlear nerve via the internal auditory canal.
对14例拉姆齐-亨特综合征患者进行了增强磁共振成像（MRI）检查，以研究该综合征的发病机制。所有MRI检查均在0.5T超导MRI系统上使用头部线圈并注射钆喷酸葡胺（Gd-DTPA）进行。许多患者在内耳道远端和迷路段区域观察到强化，在患有眩晕、耳鸣和听力损失的患者中尤为明显。在一些患者中，不仅内耳道的面神经有强化，耳蜗神经和前庭神经也有强化。由于拉姆齐-亨特综合征患者面神经的组织学变化被认为发生在内耳道远端和迷路段，该部位比膝状神经节更靠近近端，因此提示炎症可能通过内耳道扩散至前庭神经和耳蜗神经。
