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钆喷酸葡胺增强磁共振成像在贝尔面瘫和耳带状疱疹中的应用:综述及对未来研究的启示

Gd-DPTA enhanced MRI in Bell's palsy and herpes zoster oticus: an overview and implications for future studies.

作者信息

Jonsson L, Tien R, Engström M, Thuomas K A

机构信息

Department of Oto-Rhino-Laryngology, Uppsala University, Akademiska sjukhuset, Sweden.

出版信息

Acta Otolaryngol. 1995 Sep;115(5):577-84. doi: 10.3109/00016489509139371.

Abstract

Magnetic resonance imaging (MRI) is a new and important tool for use in diagnosing and investigating diseases affecting the facial nerve. In recent gadolinium-DTPA enhanced MRI (Gd-MRI) studies it has unequivocally been demonstrated that ipsilateral facial nerve contrast enhancement, predominantly in the meatal portion, is present in both Bell's palsy and herpes zoster oticus. In this overview, the results of MRI studies performed on patients with acute peripheral facial palsy, especially Bell's palsy and herpes zoster oticus, are discussed. The Gd-MRI pattern in Bell's palsy is very similar to that seen in herpes zoster oticus, and the findings reported so far support the theory that an inflammation may be the cause of the nerve injury in both cases. So far, however, Gd-MRI has not been helpful in evaluating the severity and/or prognosis of the facial palsy. Further studies employing improved techniques, including three-dimensional fast (or turbo) spin echo (3DFSE) MRI with heavily T2-weighted sections and high resolution three-dimensional Fourier transform (3DFT) MRI, need to be conducted in order to determine whether it is possible to follow the course of the disease and whether MRI and/or Gd-MRI are useful prognostic tools in the early stages of palsy.

摘要

磁共振成像(MRI)是用于诊断和研究影响面神经疾病的一种新的重要工具。在最近的钆-二乙三胺五乙酸增强MRI(Gd-MRI)研究中,已明确证实贝尔麻痹和耳带状疱疹患者均存在同侧面神经对比增强,主要在耳道部分。在本综述中,讨论了对急性周围性面神经麻痹患者,特别是贝尔麻痹和耳带状疱疹患者进行MRI研究的结果。贝尔麻痹的Gd-MRI表现与耳带状疱疹非常相似,目前报道的结果支持这样一种理论,即炎症可能是这两种情况下神经损伤的原因。然而,到目前为止,Gd-MRI在评估面神经麻痹的严重程度和/或预后方面并无帮助。需要采用改进技术进行进一步研究,包括具有重T2加权切片的三维快速(或涡轮)自旋回波(3DFSE)MRI和高分辨率三维傅里叶变换(3DFT)MRI,以确定是否有可能追踪疾病进程,以及MRI和/或Gd-MRI在麻痹早期是否为有用的预后工具。

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