Murao S, Nagai M, Sasaki K, Tokuda M, Tasaka T, Murata M, Inoo M, Ikeda K, Takahara J
First Dept. of Internal Medicine, Kagawa Medical School.
Gan To Kagaku Ryoho. 1993 Mar;20(4):529-32.
A case of acute non-lymphocytic leukemia who relapsed 7 years after the first remission is reported. The leukemic cells at onset had mature monocytic features with positive reactions for anti-CD14 antibody and alpha-NBE staining. By contrast, leukemic cells at relapse showed distinct morphological features from those at onset and lost their monocytic characters. No karyotypic abnormalities were found, but we could not exclude the possibility of secondary leukemia induced by the initial anti-leukemic chemotherapy.
