Mills N L, Everson C T, Hockmuth D R
Department of Surgery, Cardiology Center, New Orleans, Louisiana 70072.
Ann Thorac Surg. 1993 Mar;55(3):792-800. doi: 10.1016/0003-4975(93)90304-z.
The resulting abnormal geometry after surgical treatment of left ventricular aneurysm has concerned a number of surgeons since the first successful repair in 1958, but little attention was placed on the altered geometry until attempts were made to effect a more physiologic aneurysmorrhaphy in 1973. Substantial attention was focused on a concept of geometric reconstruction from within the left ventricle in 1985. A prosthetic patch was employed with the concept to redirect normal muscle bundles to their original orientation and position. Further refinements include use of improved materials for the repair, preservation and bypass of the left anterior descending coronary artery, ablation of ventricular arrhythmias when indicated, and the absence of prosthetic material used in contact with the pericardial surface. Our experience with repair of 61 left ventricular aneurysms at West Jefferson Medical Center over a 4 1/2-year period with a 3.3% mortality rate has prompted a change from the standard linear repair to routine use of a modified endoventricular repair. Currently, the low surgical risk due to advances in left ventricular aneurysmorrhaphy combined with the knowledge that contractile areas will progressively deteriorate in ventricles stressed by poor hemodynamics and with data showing improved left ventricular function postoperatively have led to more liberal recommendations for early left ventricular aneurysm repair.
自1958年首次成功修复左心室动脉瘤以来,手术治疗后所产生的异常几何形态便引起了许多外科医生的关注,但直到1973年尝试进行更符合生理的动脉瘤缝合术之前,人们对这种改变的几何形态关注甚少。1985年,大量注意力集中在了从左心室内进行几何重建的概念上。采用了人工补片,其理念是将正常肌束重新引导至其原始方向和位置。进一步的改进包括使用改良材料进行修复、保留和绕过左前降支冠状动脉、在有指征时消融室性心律失常,以及避免使用与心包表面接触的人工材料。我们在西杰斐逊医疗中心4年半的时间里对61例左心室动脉瘤进行修复的经验,死亡率为3.3%,促使我们从标准的线性修复转变为常规使用改良的心室内修复。目前,由于左心室动脉瘤缝合术的进展,手术风险较低,再加上认识到在血流动力学不佳的心室中,收缩区域会逐渐恶化,以及数据显示术后左心室功能有所改善,因此对于早期左心室动脉瘤修复的建议更加宽松。