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MHC II类区域中基因的结构与功能

Structure and function of genes in the MHC class II region.

作者信息

Monaco J J

机构信息

Department of Microbiology and Immunology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0678.

出版信息

Curr Opin Immunol. 1993 Feb;5(1):17-20. doi: 10.1016/0952-7915(93)90075-4.

Abstract

Genes required for antigen processing map to the MHC class II region. For the endogenous (class I) antigen processing pathway, many hypotheses concerning the structure and function of the corresponding gene products have been verified during the past year. The identity of the gene(s) involved in the exogenous (class II) pathway remains to be determined.

摘要

抗原加工所需的基因定位于MHC II类区域。对于内源性(I类)抗原加工途径,在过去一年里,许多关于相应基因产物的结构和功能的假说已得到验证。参与外源性(II类)途径的基因的身份仍有待确定。

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