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癫痫发作作为儿童脑肿瘤的首发症状。

Seizures as the presenting symptom of brain tumors in children.

作者信息

Sjörs K, Blennow G, Lantz G

机构信息

Department of Pediatrics, University Hospital Lund, Sweden.

出版信息

Acta Paediatr. 1993 Jan;82(1):66-70. doi: 10.1111/j.1651-2227.1993.tb12519.x.

Abstract

Epileptic seizures caused by tumors in children have been regarded as uncommon. We have studied 99 consecutive cases of brain tumors during the period 1980-1987. In 20 cases the tumor was localized to one of the hemipheres and 10 of the cases had seizures, in 9 as the only initial symptom. Details of the clinical picture and the course are presented. Delay from initial symptoms to correct diagnosis was considerable in 4 cases--more than six years. The factors mainly responsible for this delay were: initial EEG normal or soon normalized, misinterpretation of computerized tomography and seizure freedom with or without antiepileptic drug treatment. We conclude that regional slowing in the EEG is a common, although not obligatory, finding. Computerized tomography should be performed in all children with newly presented epilepsy of partial type, except for those with benign partial epilepsy with centro-temporal spikes.

摘要

儿童因肿瘤引起的癫痫发作一直被认为并不常见。我们研究了1980年至1987年间连续的99例脑肿瘤病例。其中20例肿瘤局限于一侧半球,10例出现癫痫发作,9例以癫痫发作为唯一首发症状。文中呈现了临床表现和病程的详细情况。4例从首发症状到正确诊断的延迟相当长——超过6年。造成这种延迟的主要因素有:初始脑电图正常或很快恢复正常、对计算机断层扫描的误判以及使用或未使用抗癫痫药物治疗情况下癫痫发作停止。我们得出结论,脑电图区域性减慢是一种常见表现,尽管并非必然出现。对于所有新出现部分性癫痫的儿童,除了伴有中央颞区棘波的良性部分性癫痫患者外,均应进行计算机断层扫描。

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