重新评估小儿患者周期性一侧性癫痫样放电的临床意义

Reassessment of the clinical significance of periodic lateralized epileptiform discharges in pediatric patients.

作者信息

Raroque H G, Wagner W, Gonzales P C, Leroy R F, Karnaze D, Riela A R, Roach E S

机构信息

Department of Neurology, University of Texas Southwestern Medical Center, Dallas 75235.

出版信息

Epilepsia. 1993 Mar-Apr;34(2):275-8. doi: 10.1111/j.1528-1157.1993.tb02410.x.

DOI:10.1111/j.1528-1157.1993.tb02410.x

PMID:8453936

Abstract

A review of clinical data from 18 pediatric patients with periodic lateralized epileptiform discharges and bilateral independent periodic lateralized epileptiform discharges (PLEDs and BIPLEDs) showed 2 with chronic neurologic illness, 6 with a history of prior seizures, 14 with depressed sensorium at the time of EEG, 5 deaths, and 8 of 13 survivors with neurologic deficits. These findings are similar to the combined data from reports involving adult patients only. Separating pediatric patients with PLEDs from those with BIPLEDs shows some influence from patients with BIPLEDs. Overall, our data do not suggest significant clinical differences for PLEDs between children and adults.

摘要

一项对18例患有周期性一侧性癫痫样放电和双侧独立周期性一侧性癫痫样放电（PLEDs和BIPLEDs）的儿科患者临床数据的回顾显示，2例患有慢性神经疾病，6例有既往癫痫发作史，14例在脑电图检查时存在意识障碍，5例死亡，13名幸存者中有8例存在神经功能缺损。这些发现与仅涉及成年患者的报告中的综合数据相似。将患有PLEDs的儿科患者与患有BIPLEDs的患者分开显示，BIPLEDs患者有一定影响。总体而言，我们的数据并未表明儿童和成人的PLEDs在临床方面存在显著差异。