马的标记基因。群体特异性成分（Gc）的多态性。

Equine markers genes. Polymorphism for group-specific component (Gc).

作者信息

Weitkamp L R

出版信息

Anim Blood Groups Biochem Genet. 1978;9(2):123-6. doi: 10.1111/j.1365-2052.1978.tb01422.x.

DOI:10.1111/j.1365-2052.1978.tb01422.x

PMID:84540

Abstract

Polymorphism of equine Gc protein was demonstrated by immunofixation electrophoresis with a goat anti-human Gc antibody. Three different phenotypes, F, FS and S, were found. Family data supported the genetic theory of two autosomal codominant alleles, GcF and GcS. Both alleles occurred in Standardbred, Thoroughbred and Arabian horses and in Shetland ponies. A frequency of 0.23 for GcS in the American Standardbred horse indicates the system should be useful for problems of identification and parentage.

摘要

用山羊抗人Gc抗体通过免疫固定电泳法证实了马Gc蛋白的多态性。发现了三种不同的表型，即F、FS和S。家系数据支持两个常染色体共显性等位基因GcF和GcS的遗传理论。这两个等位基因存在于标准赛马、纯种马、阿拉伯马以及设得兰矮种马中。在美国标准赛马中GcS的频率为0.23，这表明该系统在鉴定和亲子关系问题上应会有用。

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