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[不育夫妇自然受孕,与治疗无关]

[Spontaneous pregnancy, independent of treatment, in sterile couples].

作者信息

Bustos López H H, Villanueva Diaz C, Garza Rios P, Gaona R, Kably Ambe A

机构信息

Clínica de Esterilidad, Instituto Nacional de Perinatología, Méx., D.F.

出版信息

Ginecol Obstet Mex. 1993 Mar;61:60-5.

PMID:8454218
Abstract

The spontaneous pregnancy independent of treatment in sterility is a frequently observed event in this group of couples. The spontaneous pregnancy appears up to 61% of women with antecedents of sterility and in selected populations of healthy women; a third of them experience, once in their lives a subfertility episode. The characterization of this event in a population with sterility, will help to define the capacity of different diagnostic methods, as well as therapeutic methods in terms of efficacy. The objective of this study was to identify women with diagnosis of sterility and spontaneous pregnancy; to describe the main characteristics: clinical, of laboratory, of gabinet, and to discuss some implications of biological variability useful in the interpretation of these tests. One hundred and eleven patients with sterility and spontaneous pregnancy, in a descriptive and retrospective design, were analyzed. Operational definitions for the main factors related with sterility, were used, as tuboperitoneal, endocrine-ovarian, cervico-vaginal and masculine. The pregnant patients related to any type of treatment, were excluded. Two study groups were established: Group I (n-46) and Group II (n = 65) with primary sterility and secondary sterility, respectively. Average age for both groups was similar (mean = 29 years old). The time of sterility was 46.52 and 43.52 months, for Group I and II, respectively. The time of pregnancy from the point zero (admission), was, in average 6.21 and 4.9 months for Group I and II. The following factors were identified as abnormal: endocrine-ovarian 28.60 by menstrual pattern, progesterone and endometrial biopsy: tuboperitoneal 12.67% by hysterosalpingography and laparoscopy; masculine 12.67 by direct spermatobioscopy.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在这组夫妇中,不育症患者未经治疗而自然受孕是一种常见现象。在有不育症病史的女性以及特定的健康女性群体中,自然受孕率高达61%;其中三分之一的女性一生中曾经历过一次生育力低下阶段。在不育症人群中对这一现象进行特征描述,将有助于界定不同诊断方法以及治疗方法的疗效。本研究的目的是识别出已诊断为不育症且自然受孕的女性;描述其主要特征:临床特征、实验室特征、门诊特征,并探讨生物变异性在解释这些检查结果时的一些作用。对111例不育症且自然受孕的患者进行了描述性回顾性分析。采用了与不育症相关的主要因素的操作定义,如输卵管腹膜因素、内分泌 - 卵巢因素、宫颈 - 阴道因素和男性因素。排除了接受过任何类型治疗的怀孕患者。设立了两个研究组:第一组(n = 46)和第二组(n = 65),分别为原发性不育症组和继发性不育症组。两组的平均年龄相似(平均 = 29岁)。第一组和第二组的不育时间分别为46.52个月和43.52个月。从零点(入院)算起的怀孕时间,第一组和第二组平均分别为6.21个月和4.9个月。以下因素被确定为异常:通过月经模式、孕酮和子宫内膜活检发现内分泌 - 卵巢因素异常的占28.60%;通过子宫输卵管造影和腹腔镜检查发现输卵管腹膜因素异常的占12.67%;通过直接精子活组织检查发现男性因素异常的占12.67%。(摘要截选至250词)

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