Jones H, Allibone R O, Clarke T
Area Department of Pathology, Royal Devon Hospital, UK.
Histopathology. 1993 Feb;22(2):169-72. doi: 10.1111/j.1365-2559.1993.tb00097.x.
Intracorneal melanin is a feature quite frequently encountered in a range of melanocytic lesions, yet has rarely been described in the literature. We examined a variety of melanocytic lesions with increasing degrees of melanocytic atypia for this feature. The distribution and amount of intracorneal melanin is described and it was shown to be entirely within keratinocytes. In general, the amount of intracorneal melanin was related to increasing melanocytic atypia and was typically distributed in a disorderly fashion in malignant lesions.
角膜内黑色素是一系列黑素细胞性病变中相当常见的特征，但在文献中很少被描述。我们检查了各种黑素细胞性病变，观察该特征在黑素细胞异型性程度增加时的情况。描述了角膜内黑色素的分布和数量，并表明其完全存在于角质形成细胞内。一般来说，角膜内黑色素的数量与黑素细胞异型性增加有关，并且在恶性病变中通常呈无序分布。
