DXS539，一种位于脆性X基因近端的多态性DNA标记。
DXS539, a polymorphic DNA marker proximal of the fragile-X gene.
作者信息
Dreesen J C, van den Hurk J A, Smits A P, van den Ouweland A M, Markslag P W, van Oost B A
机构信息
Department of Human Genetics, University Hospital Nijmegen, The Netherlands.
出版信息
Hum Genet. 1993 Mar;91(1):80-2. doi: 10.1007/BF00230229.
We report a new polymorphic DNA marker (pJH89, DXS539) proximal to the fragile-X site. The pJH89 probe identifies a TaqI and a NcoI restriction fragment length polymorphism (combined heterozygosity of 42%) and is linked to the fragile-X locus with a maximal LOD score of 12 at 4 cM. Multipoint linkage analysis and physical mapping studies indicate that the pJH89 probe is located within in the interval defined by the markers DXS369 and DXS548.
我们报道了一种新的多态性DNA标记（pJH89，DXS539），其位于脆性X位点附近。pJH89探针可识别一种TaqI和一种NcoI限制性片段长度多态性（联合杂合度为42%），并且与脆性X位点连锁，在4厘摩处的最大优势对数（LOD）得分为12。多点连锁分析和物理图谱研究表明，pJH89探针位于由标记DXS369和DXS548所界定的区间内。
Zotero 插件