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氯化铵处理对人效应细胞在抗体依赖性和自发细胞介导的细胞毒性中活性的影响评估。

Evaluation of the effect of ammonium chloride treatment on the activity of human effector cells in antibody-dependent and spontaneous cell-mediated cytotoxicity.

作者信息

Santoli D, Trinchieri G

出版信息

J Immunol Methods. 1977;15(1):97-100. doi: 10.1016/0022-1759(77)90020-5.

Abstract

The effect of ammonium chloride treatment, used to eliminate contaminating red blood cells from lymphoid cell preparations, on the cytotoxic activity of human effector cells in antibody-dependent and spontaneous cell-mediated cytotoxicity was quantitatively determined. No significant difference between the cytotoxic efficiency of treated and untreated cell preparations was observed.

摘要

为了从淋巴细胞制剂中去除污染的红细胞,使用氯化铵处理,定量测定了其对人效应细胞在抗体依赖性和自发细胞介导的细胞毒性中的细胞毒活性的影响。未观察到处理组和未处理组细胞制剂的细胞毒性效率有显著差异。

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