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软性隐形眼镜消毒系统对一种真菌污染物的比较疗效

Comparative efficacies of soft contact lens disinfection systems against a fungal contaminant.

作者信息

Richardson L E, Begley C G, Keck G K

机构信息

Indiana University School of Optometry, Bloomington 47405.

出版信息

J Am Optom Assoc. 1993 Mar;64(3):210-4.

PMID:8454840
Abstract

The efficacies of five FDA-approved soft contact lens disinfecting solutions and heat disinfection were evaluated against the mold, Beauveria bassiana. Beauveria bassiana is a ubiquitous soil fungus with a demonstrated ability to grow into a soft contact lens matrix. A stock solution of the fungus was prepared and aliquots were added to each of the following disinfection solutions: ReNu Multi-Purpose Disinfecting Solution, Opti-Free, AOSEPT Disinfection/Neutralization Solution, Lens Plus Oxysept 1, UltraCare, and a Softmate Thermal Disinfecting Unit. Hydrogen peroxide systems were neutralized immediately using the manufacturer's recommended method. After 1 min, 5 mins, 15 mins, 30 mins, 1 hour, 4 hours, and 8 hours; samples were removed, added to neutralizing broth, and streaked onto Sabouraud's Dextrose Agar plates. Our results showed that hydrogen peroxide and heat disinfection were much more effective against Beauveria bassiana than Opti-Free or ReNu.

摘要

评估了五种美国食品药品监督管理局(FDA)批准的软性隐形眼镜消毒溶液以及热消毒对球孢白僵菌霉菌的效果。球孢白僵菌是一种普遍存在于土壤中的真菌,已证明其有能力生长到软性隐形眼镜基质中。制备了真菌储备溶液,并将等分试样添加到以下每种消毒溶液中:润明多功能消毒护理液、傲滴、AOSEPT消毒/中和溶液、乐敦清氧洁1、优能护理液,以及一个Softmate热消毒装置。使用制造商推荐的方法立即中和过氧化氢系统。在1分钟、5分钟、15分钟、30分钟、1小时、4小时和8小时后;取出样品,添加到中和肉汤中,并划线接种到沙氏葡萄糖琼脂平板上。我们的结果表明,过氧化氢和热消毒对球孢白僵菌的效果比傲滴或润明要有效得多。

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