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用于分段适形放射治疗的直线加速器评估。

Assessment of a linear accelerator for segmented conformal radiation therapy.

作者信息

Zacarias A S, Lane R G, Rosen I I

机构信息

Department of Radiation Therapy, University of Texas Medical Branch, Galveston.

出版信息

Med Phys. 1993 Jan-Feb;20(1):193-8. doi: 10.1118/1.597084.

Abstract

Segmented conformal radiation therapy is a new computer-controlled treatment technique under investigation in which the target volume is subdivided into thick transverse segments each of which is then treated individually by rectangular transverse abutting fields. In order to obtain uniform dose at abutments, the machine isocenter remains fixed in the patient and field edges are defined by independently moving focused collimator jaws to give matching geometric divergence. Mechanical variation in jaw and gantry positioning will create some dose variation at field abutments. Film dosimetry was used to study the radiation field positioning accuracy and precision of a commercial linear accelerator. A method of field position calibration was developed using multiple nonabutting fields exposed on the same radiograph. Verification of collimator jaw calibration measurements was performed using multiple abutting fields exposed on a single radiograph. Measurements taken over 5 months of clinical accelerator operation studied the effects of simple jaw motion, simple gantry motion, and combined jaw/gantry motion on jaw position precision and accuracy. The inherent precision and accuracy of radiation field positioning was found to be better than +/- 0.3 mm for both jaws with all types of motions except for the Y2 jaw under combined jaw/gantry motion. When the ability to deliver abutting beams was verified in clinical mode, the average dose variation at abutments was less than 6% at all gantry angles except for one. However, due to accelerator software limitations in clinical mode, the settings for collimator positions could not take advantage of the maximum accuracy of which the hardware is capable.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

分段适形放射治疗是一种正在研究中的新型计算机控制治疗技术,在该技术中,靶区被细分为厚的横向段,然后每个横向段通过矩形横向相邻野分别进行治疗。为了在相邻野处获得均匀剂量,机器等中心在患者体内保持固定,野边缘通过独立移动聚焦准直器钳口来定义,以提供匹配的几何发散。钳口和机架定位的机械变化会在野相邻处产生一些剂量变化。使用胶片剂量测定法研究了商用直线加速器的辐射野定位精度和准确性。利用在同一张射线照片上曝光的多个不相邻野开发了一种野位置校准方法。使用在单张射线照片上曝光的多个相邻野对准直器钳口校准测量进行验证。在临床加速器运行的5个月期间进行的测量研究了单纯钳口运动、单纯机架运动以及钳口/机架联合运动对钳口位置精度和准确性的影响。发现除了在钳口/机架联合运动下的Y2钳口外,对于所有类型的运动,两个钳口的辐射野定位固有精度和准确性均优于±0.3毫米。在临床模式下验证相邻射束的输送能力时,除一个角度外,在所有机架角度下相邻野处的平均剂量变化均小于6%。然而,由于临床模式下加速器软件的限制,准直器位置的设置无法利用硬件所能达到的最大精度。(摘要截短为250字)

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