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吸烟习惯与冠心病风险,尤其是与低日烟草消费量相关的风险

[Smoking habits and risk of coronary heart disease, especially risk associated with low daily tobacco consumption].

作者信息

Kirchhoff M, Schroll M, Hagerup L, Larsen S

机构信息

Befolkningsundersøgelserne, Københavns Amts Sygehus i Glostrup.

出版信息

Ugeskr Laeger. 1993 Mar 8;155(10):718-21.

PMID:8456515
Abstract

The purpose of this study was to estimate the risk of acute myocardial infarction related to smoking habits, especially the risk among smokers with a daily tobacco consumption of five grams or less. The study is based on data from the 1914 population examined by the Glostrup Population Studies at the age of 50 and 60 in 1964 and 1974. Information concerning deaths and cases of hospitalisation has been obtained from national registers up to 1985. Blood pressure, lipids, body mass index and physical activity were used as confounders. It was not possible to make a definite conclusion for the group smoking five grams or less daily as a class, since both the size of the group and the number of myocardial infarctions within it were small. When tobacco consumption was used as a quantitative variable the risk of myocardial infarction was found to increase with increasing amount but the relation was found not to be non-linear. The best description of the tobacco-related risk of myocardial infarction was a logarithmically relation to daily tobacco consumption.

摘要

本研究的目的是评估与吸烟习惯相关的急性心肌梗死风险,尤其是每日烟草消费量为5克或更少的吸烟者的风险。该研究基于1964年和1974年格罗斯特鲁普人群研究中在50岁和60岁时接受检查的1914名人群的数据。截至1985年,有关死亡和住院病例的信息已从国家登记处获取。血压、血脂、体重指数和身体活动被用作混杂因素。对于每日吸烟量为5克或更少的这一类别群体,无法得出明确结论,因为该群体规模较小且其中心肌梗死病例数量也较少。当将烟草消费量作为定量变量时,发现心肌梗死风险随消费量增加而增加,但发现这种关系并非呈非线性。与烟草相关的心肌梗死风险的最佳描述是与每日烟草消费量呈对数关系。

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