Schistosomiasis. Infection versus disease and hypersensitivity versus immunity.
作者信息
Cheever A W
机构信息
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
出版信息
Am J Pathol. 1993 Mar;142(3):699-702.
Abstract
摘要
相似文献
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Schistosomiasis. Infection versus disease and hypersensitivity versus immunity.血吸虫病：感染与疾病、超敏反应与免疫
Am J Pathol. 1993 Mar;142(3):699-702.
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[The self-cure phenomenon in definitive hosts infected with schistosomes].[感染血吸虫的终末宿主中的自愈现象]
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Schistosome glycans and innate immunity.血吸虫聚糖与天然免疫
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The host-parasite neuroimmunoendocrine network in schistosomiasis: consequences to the host and the parasite.血吸虫病中的宿主-寄生虫神经免疫内分泌网络：对宿主和寄生虫的影响
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Acquired immunity on a schistosomiasis transmission model - fitting the data.血吸虫病传播模型中的获得性免疫——数据拟合
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Therapeutic DNA vaccine reduces schistosoma mansoni-induced tissue damage through cytokine balance and decreased migration of myofibroblasts.治疗性 DNA 疫苗通过细胞因子平衡和减少成肌纤维细胞迁移减少曼氏血吸虫诱导的组织损伤。
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Genetic factors associated with development of cerebral malaria and fibrotic schistosomiasis.与脑型疟疾和血吸虫纤维化病发展相关的遗传因素。
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Polarization of the immune response to the single immunodominant epitope of p38, a major Schistosoma mansoni egg antigen, generates Th1- or Th2-type cytokines and granulomas.对曼氏血吸虫主要虫卵抗原p38单一免疫显性表位的免疫反应极化，会产生Th1型或Th2型细胞因子和肉芽肿。
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Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni.增强的Th1反应和减弱的Th2反应协同作用，抑制曼氏血吸虫病小鼠的急性肉芽肿和纤维化反应。
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Pharmacological evidence supporting a role for IL-1, IL-2 and serotonin in the inflammation induced by Schistosoma mansoni soluble egg antigen (SEA) in rat paws.支持白细胞介素-1、白细胞介素-2和血清素在曼氏血吸虫可溶性虫卵抗原（SEA）诱导的大鼠爪部炎症中起作用的药理学证据。
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Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology.内源性白细胞介素12（IL-12）调节曼氏血吸虫虫卵诱导的肉芽肿形成，外源性IL-12既能抑制虫卵病理反应，又能起到预防性免疫作用。
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本文引用的文献
1
Hepatic fibrosis in rabbits infected with Japanese and Philippine strains of Schistosoma japonicum.
Am J Trop Med Hyg. 1980 Nov;29(6):1327-39. doi: 10.4269/ajtmh.1980.29.1327.
2
3
A quantitative post-mortem study of Schistosomiasis mansoni in man.人体曼氏血吸虫病的定量尸检研究
Am J Trop Med Hyg. 1968 Jan;17(1):38-64. doi: 10.4269/ajtmh.1968.17.38.
4
Experimental infection with Schistosoma japonicum in chimpanzees.黑猩猩感染日本血吸虫的实验研究。
Am J Trop Med Hyg. 1971 Nov;20(6):850-93. doi: 10.4269/ajtmh.1971.20.850.
5
Quantitative comparison of the intensity of Schistosoma mansoni infections in man and experimental animals.
Trans R Soc Trop Med Hyg. 1969;63(6):781-95. doi: 10.1016/0035-9203(69)90122-9.
6
Schistosomiasis mansoni in the chimpanzee. The natural history of chronic infections after single and multiple exposures.黑猩猩中的曼氏血吸虫病。单次和多次接触后的慢性感染自然史。
Am J Trop Med Hyg. 1970 Mar;19(2):258-77.
7
Pathogenesis of pipe-stem fibrosis of the liver (experimental observation on murine schistosomiasis).肝管道型纤维化的发病机制（小鼠血吸虫病的实验观察）
Mem Inst Oswaldo Cruz. 1987 Jul-Sep;82(3):325-34. doi: 10.1590/s0074-02761987000300003.
8
Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.两种小鼠辅助性T细胞克隆。II. 迟发型超敏反应由TH1克隆介导。
J Immunol. 1987 Jun 1;138(11):3688-94.
9
Gamma-interferon treatment inhibits collagen deposition in murine schistosomiasis.γ-干扰素治疗可抑制小鼠血吸虫病中的胶原蛋白沉积。
Hepatology. 1989 Nov;10(5):795-800. doi: 10.1002/hep.1840100508.
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