Agüero A, Arnedo M, Gallo M, Puerto A
Departamento de Psicología Experimental y Fisiología del Comportamiento, Universidad de Granada, Spain.
Brain Res Bull. 1993;30(5-6):585-92. doi: 10.1016/0361-9230(93)90086-q.
The research about the neural basis of taste aversion learning (TAL) has pointed out the area postrema (AP) as a fundamental structure implied in the processing of certain toxic stimuli. Likewise, recent studies demonstrated that electric stimulation of the AP is an efficient substitute of the aversive stimulus. The lateral parabrachial nucleus (PBN1), one of the subnuclei of the parabrachial complex, is the main anatomic rostral connection of the AP. In the experiment presented here, we demonstrate that TAL induced by electric stimulation of the AP is interrupted when the PBN1 is lesioned, thus giving support to the functional role of this anatomic system (AP-PBN1) in the codification of aversive stimuli processed by the AP.
关于味觉厌恶学习（TAL）神经基础的研究指出，最后区（AP）是参与某些毒性刺激处理的重要结构。同样，最近的研究表明，对AP进行电刺激是厌恶刺激的有效替代方法。臂旁复合体的一个亚核——外侧臂旁核（PBN1）是AP主要的解剖学上的嘴侧连接。在本文介绍的实验中，我们证明，当PBN1受损时，由AP电刺激诱导的TAL会中断，从而支持了这个解剖系统（AP-PBN1）在由AP处理的厌恶刺激编码中的功能作用。
