Williams D N, Bosch D, Boots J, Schneider J
Methodist Hospital, St. Louis Park, MN.
Clin Ther. 1993 Jan-Feb;15(1):169-79; discussion 168.
We analyzed the costs of an outpatient intravenous (IV) treatment program using a broad-spectrum, third-generation cephalosporin. Fifty-six patients were treated for various infections in a hospital-based outpatient IV antibiotic program. The mean length of outpatient treatment was 7.4 days (range, 2 to 24 days). Infections in 53 patients resolved successfully, with only 3 patients experiencing recurrence. Side effect were minimal, with no significant toxicities; one case of oral candidiasis and one case of rash occurred. Collectively, the 56 patients were treated for 286 days in the hospital and 414 days in an outpatient program. Costs were totaled on a weekly basis and divided by seven to arrive at a daily charge; the antibiotic most frequently prescribed was used as the representative regimen. The mean cost for each hospital day was $417 compared with $155 per outpatient day, a savings of $262 on a daily basis. We conclude that outpatient IV antibiotic therapy is safe and effective for a variety of infections in a wide range of patients and can contribute to substantial financial savings.
我们分析了使用广谱第三代头孢菌素的门诊静脉注射（IV）治疗方案的成本。56名患者在一个以医院为基础的门诊静脉抗生素治疗方案中接受了各种感染的治疗。门诊治疗的平均时长为7.4天（范围为2至24天）。53名患者的感染成功治愈，只有3名患者出现复发。副作用轻微，无明显毒性；发生了1例口腔念珠菌病和1例皮疹。56名患者在医院共接受了286天的治疗，在门诊治疗方案中接受了414天的治疗。成本按周计算并除以7得出每日费用；最常开具的抗生素被用作代表性治疗方案。住院每天的平均费用为417美元，而门诊每天为155美元，每天节省262美元。我们得出结论，门诊静脉抗生素治疗对于广泛患者的各种感染是安全有效的，并且可以大幅节省费用。
