Janousková K, Tĕsínský P, Topolcan O
Ocní klinika lékarské fakulty UK, Plzen.
Cesk Oftalmol. 1993 Jan;49(1):13-21.
This paper deals with the relation of disorders of carbohydrate metabolism to etiopathogenesis of glaucoma. 102 patients with primary glaucoma of an open angle were examined and it was discovered that 80 patients from this group (78%) had an abnormal immuno-reactive insulin curve, in particular of the hypersecretory type. Standard gauge test for abnormal glucose level was administered with 31 glaucomatous patients (30%). From this point of view screening for immuno-reactive insulin is a more sensitive and reliable method than the glucose standard gauge test. It is recommended that testing for immuno-reactive insulin should be introduced for all glaucomatous patients because this can help both in the detection of early stages of diabetes and in the administration of primary prevention of atherosclerosis among the population.
本文探讨了碳水化合物代谢紊乱与青光眼病因发病机制之间的关系。对102例原发性开角型青光眼患者进行了检查,发现该组中有80例患者(78%)免疫反应性胰岛素曲线异常,尤其是高分泌型。对31例青光眼患者(30%)进行了血糖水平异常的标准测量试验。从这一角度来看,免疫反应性胰岛素筛查是一种比血糖标准测量试验更敏感、更可靠的方法。建议对所有青光眼患者进行免疫反应性胰岛素检测,因为这有助于早期发现糖尿病,并对人群中的动脉粥样硬化进行一级预防。