Janousková K, Tĕsínský P, Topolcan O
Ocní klinika lékarské fakulty UK, Plzen.
Cesk Oftalmol. 1993 Jan;49(1):22-9.
Observing interrelation between carbohydrate metabolism disorders and contrainsular mechanisms in a group of 102 glaucomatous patients, a higher level of cortisol in plasma was detected in 40.2% of glaucomatous patients of whom 31% had increased levels of cortisol together with IRI. In isolation the increased level of cortisol occurred in 8.9%. The frequency of increased cortisol level in glaucomatous patients is substantially lower (40.2%) than the frequency of abnormal insulin curves (78%). Increased levels of growth hormone in the group of patients occurred in 9.3% of cases and these were almost always associated with an abnormal immuno-reactive insulin curve (IRI curve). Accordingly, it is evident that hormonal disorders are a major factor in the onset of both diabetes and glaucoma.
在一组102名青光眼患者中观察碳水化合物代谢紊乱与抗胰岛素机制之间的相互关系，发现40.2%的青光眼患者血浆皮质醇水平较高，其中31%的患者皮质醇水平升高同时伴有免疫反应性胰岛素（IRI）升高。单独出现皮质醇水平升高的情况占8.9%。青光眼患者皮质醇水平升高的频率（40.2%）明显低于异常胰岛素曲线的频率（78%）。患者组中生长激素水平升高的情况占9.3%，且这些情况几乎总是与异常的免疫反应性胰岛素曲线（IRI曲线）相关。因此，很明显激素紊乱是糖尿病和青光眼发病的主要因素。
