Singer L, Arendt R, Minnes S
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Clin Perinatol. 1993 Mar;20(1):245-62.
How and to what extent fetal cocaine exposure produces specific, negative, long-term effects on infant neurodevelopmental competence has not yet been determined. We have argued previously that results from animal studies, the findings of intrauterine growth retardation in human studies, and the markedly higher incidence of numerous associated risk factors in cocaine-exposed cohorts herald significant clinical risk to the developing infant. Recognition of infant risk status should not imply condemnation of a group of children but, as with preterm infants, lead to aggressive, national, social, and scientific efforts to delineate and intervene with potential sequelae of drug exposure.
胎儿接触可卡因如何以及在多大程度上对婴儿神经发育能力产生特定的负面长期影响尚未确定。我们之前曾指出，动物研究的结果、人类研究中宫内生长迟缓的发现，以及可卡因暴露队列中众多相关风险因素的明显更高发生率，预示着发育中的婴儿面临重大临床风险。认识到婴儿的风险状况并不意味着对一群儿童的谴责，而是应像对待早产儿一样，促使国家、社会和科学界积极努力，以明确并干预药物暴露的潜在后遗症。
