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Rat intestinal epithelial cell line IEC-6 is activated by recombinant interferon-gamma to inhibit replication of the coccidian Toxoplasma gondii.

作者信息

Dimier I H, Bout D T

机构信息

Unité de Recherche Université-INRA d'Immunologie Parasitaire, UFR des Sciences Pharmaceutiques de Tours, France.

出版信息

Eur J Immunol. 1993 Apr;23(4):981-3. doi: 10.1002/eji.1830230435.

DOI:10.1002/eji.1830230435
PMID:8458385
Abstract

Toxoplasma gondii tachyzoites invaded and replicated in cultured rat small intestine cells of the line IEC-6. Treatment of rat small intestine cells with murine recombinant interferon-gamma resulted in a dose-dependent inhibition of intracellular T. gondii replication. This could be of relevance as a first line defense against Toxoplasma infection.

摘要

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