Moulin A, Collet L, Veuillet E, Morgon A
Université Claude Bernard, Laboratoire de Physiologie Sensorielle Audition et Voix, Unité associée au CNRS 1447, Hôpital Edouard Herriot, Lyon, France.
Hear Res. 1993 Feb;65(1-2):216-33. doi: 10.1016/0378-5955(93)90215-m.
Active cochlear mechanisms and especially outer hair cells seem to be involved in oto-acoustic emissions (OAEs) genesis. This study sought to investigate basic characteristics of spontaneous otoacoustic emissions (SOAEs), click-evoked otoacoustic emissions (TOAEs) and interrelations between SOAEs, TOAEs and 2f1-f2 and 2f2-f1 distortion product OAEs (DPOAEs) in 135 normally hearing subjects. A gender effect was shown on TOAEs and DPOAEs amplitude, and is attributed to the higher incidence of SOAEs in women (58%) than in men (22%). Moreover, SOAEs presence seems to mask the age effect found, especially at high frequency components, on TOAEs amplitude. A general influence of SOAEs on TOAEs and DPOAEs is shown, especially at frequencies ranging from 1 kHz to 3 kHz, collecting more than 66% of the SOAEs peaks recorded. Lastly, correlations between TOAEs frequency band amplitude and 2f1-f2 DPOAEs amplitude, shows frequency specificity, at least at low frequencies (i.e., from 0.5 to 2 kHz) in agreement with previous works suggesting that the 2f1-f2 DPOAEs generation site is at the geometric mean of the primaries. The same correlations calculated with 2f2-f1 DPOAEs amplitude show frequency specificity at low frequencies i.e., at 800 Hz and 1600 Hz. 2f2-f1 DPOAEs in humans are shown to be generated near the 2f2-f1 frequency region on the cochlear partition.
活跃的耳蜗机制,尤其是外毛细胞,似乎与耳声发射(OAE)的产生有关。本研究旨在调查135名听力正常受试者的自发性耳声发射(SOAE)、短声诱发耳声发射(TOAE)的基本特征,以及SOAE、TOAE与2f1 - f2和2f2 - f1畸变产物耳声发射(DPOAE)之间的相互关系。研究发现TOAE和DPOAE振幅存在性别效应,这归因于女性中SOAE的发生率(58%)高于男性(22%)。此外,SOAE的存在似乎掩盖了在TOAE振幅上发现的年龄效应,尤其是在高频成分中。研究表明SOAE对TOAE和DPOAE有普遍影响,特别是在1 kHz至3 kHz的频率范围内,该范围内收集到的SOAE峰值超过66%。最后,TOAE频段振幅与2f1 - f2 DPOAE振幅之间的相关性显示出频率特异性,至少在低频(即0.5至2 kHz)时如此,这与之前的研究结果一致,即2f1 - f2 DPOAE的产生部位在两个原始频率的几何平均值处。用2f2 - f1 DPOAE振幅计算的相同相关性在低频(即800 Hz和1600 Hz)时也显示出频率特异性。研究表明,人类的2f2 - f1 DPOAE是在耳蜗隔板上2f2 - f1频率区域附近产生的。