von Reyn C F, Gilbert T T, Shaw F E, Parsonnet K C, Abramson J E, Smith M G
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.
JAMA. 1993 Apr 14;269(14):1807-11. doi: 10.1001/jama.269.14.1807.
To determine the risk of human immunodeficiency virus (HIV) transmission from an HIV-infected orthopedic surgeon to patients undergoing invasive procedures.
Retrospective epidemiologic follow-up study.
A total of 2317 former patients on whom the orthopedic surgeon performed invasive procedures between January 1, 1978, and June 30, 1991 [corrected].
HIV infection or death from an acquired immunodeficiency syndrome (AIDS)-defining tumor or opportunistic infection.
An orthopedic surgeon voluntarily withdrew from practice after testing positive for HIV. Testing for HIV was performed on 1174 former patients, representing 50.7% of patients on whom the orthopedic surgeon performed invasive procedures during the 13.5-year period. Patients were tested from each year and from each category of invasive procedure. All patients were HIV-negative by enzyme-linked immunosorbent assay. Two former patients reported known HIV infection prior to surgery. Review of AIDS case registries and vital records failed to detect cases of HIV infection among former surgical patients. The estimated cost of the initial patient notification and testing was $158,500. The patient notification and testing were conducted while maintaining the confidentiality of the orthopedic surgeon who was an active participant in the planning and execution of the study.
The risk of HIV transmission from an HIV-infected surgeon who adheres to recommended infection control practices is extremely low. Notification and HIV testing of former patients in this setting is both disruptive and expensive and is not routinely recommended.
确定人类免疫缺陷病毒(HIV)从一名感染HIV的骨科医生传播给接受侵入性操作患者的风险。
回顾性流行病学随访研究。
1978年1月1日至1991年6月30日期间,该骨科医生对其进行侵入性操作的2317名既往患者。
HIV感染或因获得性免疫缺陷综合征(AIDS)定义的肿瘤或机会性感染导致的死亡。
一名骨科医生HIV检测呈阳性后自愿停止执业。对1174名既往患者进行了HIV检测,占该骨科医生在13.5年期间进行侵入性操作患者的50.7%。对每年及各类侵入性操作的患者均进行了检测。所有患者酶联免疫吸附试验检测HIV均为阴性。两名既往患者报告术前已知感染HIV。查阅AIDS病例登记和生命记录未发现既往手术患者中有HIV感染病例。最初患者通知和检测的估计费用为158,500美元。在进行患者通知和检测时,对作为该研究积极参与者的骨科医生的信息进行了保密。
一名遵循推荐感染控制措施的感染HIV的外科医生传播HIV的风险极低。在此情况下对既往患者进行通知和HIV检测既会造成干扰又费用高昂,因此不常规推荐。