Watmough D J, Quan K M, Aspden R M
Department of BioMedical Physics and BioEngineering, University of Aberdeen, Foresterhill, Scotland.
J Biomed Eng. 1993 Mar;15(2):121-6. doi: 10.1016/0141-5425(93)90040-6.
X-Ray mammography is the technique employed to image breast tumours; it is the gold standard for both diagnosis and screening. To increase the sensitivity of the test and to reduce the dose of X-radiation, breast compression is used. The effect of squeezing a simple model of a breast in which there is an idealized spherical tumour volume is investigated; the cases where the lesion has both a smaller, and a larger compressibility than the surrounding tissues are considered. Surface strain is computed as a function of the deformation of the lesion from its spherical shape. Evidence from earlier studies is adduced to show that when the lesion is malignant care should be exercised to avoid the possibility of disseminating cancer cells by the application of compressive forces.
X射线乳房造影术是用于对乳腺肿瘤进行成像的技术；它是诊断和筛查的金标准。为了提高检测的灵敏度并减少X射线辐射剂量，采用了乳房压迫技术。研究了挤压一个具有理想化球形肿瘤体积的简单乳房模型的效果；考虑了病变的可压缩性比周围组织小和大的情况。表面应变是根据病变从球形变形的情况计算得出的。引用早期研究的证据表明，当病变为恶性时，应注意避免因施加压缩力而导致癌细胞扩散的可能性。
