Bakic Predrag R, Albert Michael, Brzakovic Dragana, Maidment Andrew D A
Department of Radiology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5563, USA.
Med Phys. 2002 Sep;29(9):2131-9. doi: 10.1118/1.1501143.
A method is proposed for generating synthetic mammograms based upon simulations of breast tissue and the mammographic imaging process. A computer breast model has been designed with a realistic distribution of large and medium scale tissue structures. Parameters controlling the size and placement of simulated structures (adipose compartments and ducts) provide a method for consistently modeling images of the same simulated breast with modified position or acquisition parameters. The mammographic imaging process is simulated using a compression model and a model of the x-ray image acquisition process. The compression model estimates breast deformation using tissue elasticity parameters found in the literature and clinical force values. The synthetic mammograms were generated by a mammogram acquisition model using a monoenergetic parallel beam approximation applied to the synthetically compressed breast phantom.
提出了一种基于乳腺组织模拟和乳腺成像过程来生成合成乳腺X线照片的方法。设计了一种计算机乳腺模型，其中包含大尺度和中尺度组织结构的真实分布。控制模拟结构（脂肪隔室和导管）大小和位置的参数提供了一种方法，可通过修改位置或采集参数对同一模拟乳腺的图像进行一致建模。使用压缩模型和X射线图像采集过程模型来模拟乳腺成像过程。压缩模型利用文献中发现的组织弹性参数和临床力值来估计乳腺变形。合成乳腺X线照片由乳腺X线照片采集模型生成，该模型使用单能平行束近似法应用于合成压缩的乳腺体模。
