一个40千碱基的亚端粒区域在大多数恶性疟原虫3D7染色体中是常见的。
A 40-kilobase subtelomeric region is common to most Plasmodium falciparum 3D7 chromosomes.
作者信息
Scotti R, Pace T, Ponzi M
机构信息
Laboratorio di Biologia Cellulare, Istituto Superiore di Sanità, Rome, Italy.
出版信息
Mol Biochem Parasitol. 1993 Mar;58(1):1-6. doi: 10.1016/0166-6851(93)90084-b.
Starting from previous evidence indicating that some features are shared by several Plasmodium falciparum chromosomal extremities, a subtelomeric region present on most P. falciparum 3D7 chromosomes has been mapped. It was shown to occupy about 40 kb, and to include the proximal portion of pPftel. 1, the only telomeric clone described for P. falciparum [12], the complete 21-bp repetitive cluster and some conserved sites (PstI, EcoRI) proximally located with respect to this cluster.
基于先前的证据表明几种恶性疟原虫染色体末端具有一些共同特征，已对大多数恶性疟原虫3D7染色体上存在的一个亚端粒区域进行了定位。结果显示该区域约占40 kb，并包括pPftel. 1的近端部分，pPftel. 1是恶性疟原虫描述的唯一端粒克隆[12]，完整的21 bp重复簇以及相对于该簇近端定位的一些保守位点（PstI、EcoRI）。
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