Holtås S, Basibüyük N, Fredriksson K
Department of Diagnostic Radiology, University Hospital, Lund, Sweden.
Neuroradiology. 1993;35(3):221-6. doi: 10.1007/BF00588501.
The MRI examinations of seven patients with acute transverse myelopathy (ATM) were analysed. The patients were examined 2-5 times during the course of their disease with short and long TR/TE spin-echo sequences in the sagittal projection. A previous history of autoimmune disorder and/or signs of infection at the onset of ATM were present in all cases. Cerebrospinal fluid analysis showed local synthesis of immunoglobulin in the nervous system in three cases and signs of infectious myelitis in one. During the acute phase four patients had local enlargement of the cord and all had increased signal on long TR/TE sequences. The outcome was grave in the majority of patients and there seemed to be a correlation between the degree of cord enlargement, persistence of increased signal intensity and limited recovery. Atrophy and remaining high signal intensity were noted on late MRI in patients with poor outcome. In one patient with probable anterior spinal artery occlusion, cavitation of the cord was seen.
对7例急性横贯性脊髓炎(ATM)患者的MRI检查结果进行了分析。在病程中,对这些患者进行了2至5次检查,采用短TR/TE和长TR/TE自旋回波序列进行矢状面成像。所有病例在ATM发病时均有自身免疫性疾病史和/或感染迹象。脑脊液分析显示,3例患者存在神经系统局部免疫球蛋白合成,1例有感染性脊髓炎迹象。急性期,4例患者脊髓局部增粗,所有患者在长TR/TE序列上信号均增强。大多数患者预后严重,脊髓增粗程度、信号增强持续时间与恢复受限之间似乎存在相关性。预后较差的患者在后期MRI检查中可见脊髓萎缩和持续的高信号强度。1例可能存在脊髓前动脉闭塞的患者,可见脊髓空洞形成。