Mazer C D
Department of Anesthesia, St. Michael's Hospital, University of Toronto, Ontario, Canada.
J Card Surg. 1993 Mar;8(2 Suppl):329-31. doi: 10.1111/j.1540-8191.1993.tb01334.x.
Calcium administration during ischemia or at the onset of reperfusion is generally considered to be deleterious because cytosolic calcium is elevated at this time. In contrast, the administration of calcium antagonists before or during ischemia is protective. While calcium antagonists may not be beneficial when given after reperfusion, calcium administration during this period has been found to enhance the recovery of systolic and diastolic function of stunned myocardium.
在缺血期间或再灌注开始时给予钙通常被认为是有害的，因为此时胞浆钙会升高。相比之下，在缺血之前或期间给予钙拮抗剂具有保护作用。虽然在再灌注后给予钙拮抗剂可能没有益处，但在此期间给予钙已被发现可增强顿抑心肌的收缩和舒张功能恢复。
