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[肺腺瘤样畸形的产前诊断。5例报告并文献复习]

[Prenatal diagnosis of adenomatoid malformation of the lung. 5 cases and review of the literature].

作者信息

Salle B, Rebaud A, Rudigoz R C, Mellier G

机构信息

Service de Gynécologie et Obstétrique, Hôpital de la Croix-Rousse, Lyon.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1993;22(1):53-7.

PMID:8463568
Abstract

The authors report five cases of adenomatoid malformation of the lung (AML) diagnosed in the antenatal period. Since 1977, when Stocker et al. published their classification of these malformations into three anatomical types, the ultrasonographic features have been well systematized, thereby enabling treatment to be modified according to the AML type. Type I and II have a good prognosis (about 20% of neonatal deaths) and only require close supervision. Thoracocentesis may be necessary in case of significant anasarca or hydramnios. The progression and prognosis of type III AML are very bad, since a favorable course is observed in only 10% of the foetuses. Intrauterine surgery has already been successfully attempted in on case and might modify the situation. Most authors are in favour of therapeutic abortion when signs of bad prognosis are present.

摘要

作者报告了5例产前诊断为肺腺瘤样畸形(AML)的病例。自1977年斯托克等人将这些畸形分为三种解剖类型以来,超声特征已得到很好的系统化,从而能够根据AML类型调整治疗方案。I型和II型预后良好(新生儿死亡率约为20%),仅需密切监测。出现明显水肿或羊水过多时可能需要胸腔穿刺。III型AML的进展和预后非常差,因为只有10%的胎儿有良好的病程。已有一例成功尝试了宫内手术,可能会改变这种情况。大多数作者赞成在出现预后不良迹象时进行治疗性流产。

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