De Santis M, Masini L, Noia G, Cavaliere A F, Oliva N, Caruso A
Department of Obstetrics and Gynecology, Catholic University of Sacred Heart, Rome, Italy.
Fetal Diagn Ther. 2000 Jul-Aug;15(4):246-50. doi: 10.1159/000021015.
Seventeen cases of congenital cystic adenomatoid malformation of the lung (CCAM) are reported. They were followed up over a period of 1 month to 15 years. Diagnosis was made by prenatal ultrasound. Our purpose was to evaluate the fetal-neonatal outcome and the prognostic elements observable through ultrasound techniques, and to compare all types of CCAM. The outcome observed ranged from total prenatal resolution to postnatal spontaneous regression of the lesion, to complications due to the presence of nonimmune fetal hydrops (NIFH), intrauterine death and the necessity of surgical intervention. In our experience only hydrops represented a negative predictor of outcome since death occurred in all cases with this pathology. In the absence of NIFH, counselling should stress the prevalence of a positive outcome, even in cases of surgical intervention.
报告了17例先天性肺囊性腺瘤样畸形（CCAM）。对其进行了1个月至15年的随访。诊断通过产前超声做出。我们的目的是评估胎儿-新生儿结局以及通过超声技术可观察到的预后因素，并比较所有类型的CCAM。观察到的结局范围从病变在产前完全消退到产后自发消退，再到因非免疫性胎儿水肿（NIFH）、宫内死亡以及手术干预的必要性而出现的并发症。根据我们的经验，只有水肿是结局的负面预测因素，因为所有患有这种病理情况的病例均发生了死亡。在没有NIFH的情况下，咨询应强调即使在手术干预的病例中，良好结局的普遍性。
